I believe some of the quests only become available when you unlock WQ’s.  I am assuming (because it happened to me in Ardenweald: guide 95% complete with no available quests).  I don’t think the quest lines are bugged, just probably some of the quests in the guide are slightly in the wrong place.  (Probably a change from the game/guide being tested in Beta to Retail).  you can X the quest to move on through the guide then un-select after the zone is completed, so you return when WQ’s are unlocked.