I’ll bump this instead of making a new. I have this same issue. Any time I accept/turn in a quest or make progress on a quest and the guide updates I get a massive frame drop. I have tried disabling all other addons, putting the guide in essential mode and it still happens.
https://clips.twitch.tv/SillyWrongRamenSuperVinlin
Its hard to see but my fps drops from 150ish to 40