This can happen if your game crashed or don’t exit the game properly by clicking logout or exit game.
Proper log out or game exit is essential for a WoW addon to save any changed settings.
Don’t close your game by clicking the Window close button or pressing ALT-F4 and Dugi Guides should save your progress.
If that didn’t resolve your issue, please note the guide and step name that gets unticked and submit a ticket and report.
Posted in: Addon & Guide Usage Questions